南予医学雑誌　第18巻

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岡田、他：パゾパニブによりCRが得られた悪性葉状腫瘍再発の１例南予医誌　Vol.18　No. １　2017－61－Abstract　A 45-year-old female visited our hospital with a right breast tumor that had gradually grown over about 20years．The tumor was 7×7㎝ in diameter and we found multiple pul-monary metastases．The tumor was resected and pathologically diagnosed as a malignant phyllodes tumor．She underwent three cycles of chemotherapy with adriamycin and ifos-famide but did not benet therefrom．She then underwent molecularly targeted therapy with pazopanib．The adverse events included hypertension，hand/foot syndrome，and thrombocytopenia，but she tolerated these well and achieved a complete response over２years．This is the rst report of a complete response to pazopanib in a patient with a meta-static，malignant，phyllodes breast tumor．（Nan-yo Med J 2017; 18: 56-61.）keyword；malignant phyllodes tumor，pazopanibA complete response to pazopanib in a patient with a metastatic, malignant, phyllodes breast tumorKenzo OKADA, Miku NAKAGAWA, Gen KANESADA, Naoki MUKAI,Yusuke NISHI, Katsuhiro TOMOFUJI, Hajime SATO, Naoki ISHIDA,Yoshinori IMAI, Jota WATANABE,Kenji NEZU, Shinsuke KAJIWARADepartment of SurgeryUwajima City HospitalGoten-machi, Uwajima, Ehime 798-8510, Japan