大蔵:血清シスタチンC測定の有用性南予医誌 Vol.14 No. 1 2013-7-(図6) シスタチンCと炎症めることにある。日本においてその検討は十分とはいえないが,実地診療の貴重な診療手段になるものと思われる。参考文献1) Rawlings ND, Barrett AJ: Evolution of proteins of the cystatin superfamily. J Mol Evol. 1990; 30: 60-71.2) Abrahamson M, Barrett AJ, Salversen G, et al. : Isolation of six cysteine pro-teinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological uids. J Biol Chem 1986; 261(24): 11282-11289.3) Grubb A: Diagnostic value of analysis of cystatin C and protein HC in bio-logical fluids. Clin Nephrol 1992; 38 Suppl 1: S20-27.4) Loöfberg H, Grubb AO: Quantitation of γ-trace in human biological uids: indications for the production in the central nervous system. Scand J Clin Lab Invest 1979; 39: 619-629.5) Simonsen O, Grubb A, Thysell H: The blood serum concentrati on of cystatin C (gamma-trace) as a measure of the glomerular ltration rate. Scand J Clin Lab Invest. 1985; 45: 97-101.6) CKD診療ガイド作成ワーキンググループ:CKD診療ガイド2009 (日本腎臓学会編),東京医学社, 20097) CKD診療ガイド作成ワーキンググループ:CKD診療ガイド2012 (日本腎臓学会編),東京医学社, 20128) Zhang Z, Lu B, Sheng X, et al.: Cys-tatin C in prediction of acute kidney injury: a systemic review and meta-analysis. Am J Kidney Dis 2011; 58: 356-365.9) Fliser D, Ritz E: Serum cystatin C con-centration as a marker of renal dys-function in the elderly. Am J Kidney Dis. 2001; 37: 79-83.図6シスタチンCと炎症Ln : log natural文献14)より引用
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