南予医学雑誌 第14巻
32/114

南予医誌 Vol.14 No. 1 2013-30-Abstract A 53-year-old woman complained of a fever and sore throat in June 2011, and she was admitted to our hospital. Laboratory ndings were as follows: TSH < 0.01 mIU/mL, FT3 = 7.55 pg/mL, FT4 = 2.91 ng/dL, TRAb = 6.2 IU/mL, AST = 260 U/L, ALT = 277 U/L, EB VCA-IgM ×80, EB VCA-IgG ×160, and EB EBNA < ×10. Thyroid ultrasonography showed diffuse goiter. The thyroid radioactive 99mTc uptake ratio was increased in both lobes. We diagnosed Graves’ disease associated with infectious mononucleosis. The pa-tient was treated orally with potassium iodide (KI) starting at 100 mg/day because of liver injury. The hyperthyroidism and elevated liver enzymes gradually recovered in the 2 weeks following admission. Laboratory ndings were as follows: TSH < 0.01 mIU/mL, FT3 = 2.72 pg/mL, FT4 = 1.13 ng/dL, AST = 54 U/L, and ALT = 90 U/L. Therefore, the KI was discontinued, and thiamazole was orally administered starting at 20 mg/day. The liver injury and thyroid function recovered to their normal ranges a few months later. These ndings suggest that EB virus may play an important role in the development of Graves’ disease. (Nan-yo Med J 2013;14:24-30.)Graves’ disease associated with infectious mononucleosis in older adults: a case reportTohru EGUCHI, Shozo MIYAUCHIDepartment of Internal MedicineUwajima City HospitalGoten-machi, Uwajima, Ehime 798-8510, JAPAN

元のページ  ../index.html#32

このブックを見る