南予医学雑誌 第15巻
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井上、他:放射線治療による腫瘍崩壊症候群例南予医誌 Vol.15 No. 1 2014-63-が,放射線療法としては低リスクではなかったと考えられる。 マントル細胞リンパ腫などの放射線感受性の極めて強い腫瘍の局所コントロールとして放射線治療を行う場合には,TLSのリスクが伴うことを考え,予防策を講じる必要があると考える。参考文献1)  Yamazaki H, Hanada M, Horiki M, et al. : Acute tumor lysis syndrome caused by palliative radiotherapy in patients with diffuse large B-cell lym-phoma. Radiation Med 2004; 22: 52-55. 2)  張替秀朗,浦野透,多田公英,他:胸壁腫瘤を形成し,放射線治療によりAcute Tumor Lysis Syndromeを呈した慢性骨髄性白血病の1例.臨床血液 1991; 32: 183-184.3)  増岡秀一,大坪寛子,西脇嘉一,他:脾臓に対する放射線療法後に腫瘍崩壊症候群を合併したCLLの1例.臨床血液 1999; 40: 350.4)  Cairo MS, Coiffier B, Reiter A, et al. : Recommendations for the evalua-tion of risk and prophylaxis of tumor lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus. Br J Haematol 2010; 149: 578-586.5)  Trobaugh-Lotrario AD, Liang X, Janik JS, et al. : Difcult diagnostic and ther-apeutic cases: CASE 2. thymoma and tumor lysis syndrome in an adolescent. J Clin Oncol 2004; 22: 955-957.6)  Rostom AY, El-Hussainy G, Kandil A, et al. : Tumor lysis syndrome follow-ing hemi-body irradiation for meta-static breast cancer. Ann Oncol 2000; 11: 1349-1351.7)  Noh GY, Choe DH, Kim CH, et al. : Fa-tal tumor lysis syndrome during radio-therapy for non-small-cell lung cancer. J Clin Oncol 2008; 26: 6005-6006.8)  Kaplan MA, Kucukoner M, Alpagat G, et al. : Tumor lysis syndrome during radiotherapy for prostate cancer with bone and bone marrow metastases without visceral metastasis. Ann Saudi Med 2012; 32: 306-308.9)  Rosenbluth BD,Yahalom J : Highly effective local control and palliation of mantle cell lymphoma with involved-field radiation therapy (IFRT). Int J Radiat Oncol Biol Phys 2006; 65: 1185-1191.10)  Joshita S, Yoshizawa K, Sano K, et al. : A patient with advanced hepatocel-lular carcinoma treated with sorafenib tosylate showed massive tumor lysis with avoidance of tumor lysis syn-drome. Intern Med 2010; 49: 991-994.11)  Krishnan G, D’Silva K, Al-Janadi A : Cetuximab-related tumor lysis syn-drome in metastatic colon carcinoma. J Clin Oncol 2008; 26: 2406-2408. 12)  Michels J, Lassau N, Gross-Goupil M, et al. : Sunitinib inducing tumor lysis syndrome in a patient treated for renal carcinoma. Invest New Drugs 2010; 28: 690-693.13)  日本臨床腫瘍学会編:腫瘍崩壊症候群(TLS)診療ガイダンス.金原出版,東京,2013.

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